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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264346b050bff1a64f7f989e2a63a2991ba124e619908f7d4aa6657acacf6f0f' 
  AND token = 'ZTwUGO04lPgbg9xDIiw2t+f/zXnDzCv5/mQMTLZ+38M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}