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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427628b85a0c85ef51b10b0871a7c038a9b6fd86ed84a7ff46344b64bde3f235' 
  AND token = 'tQQWXfVE34iJz1jCUkTGYFy/RNYTpie0urW8lYKOecU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}