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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9b47a76481bad48d5c09c1a8ea3033648ea727172232ba3b3a9762e1281aec' 
  AND token = 'zx+SXRcZPA3v1kYXDH9rF0sV3LVCk44p8Wl9hQNWkMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}