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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede13825f1cb66f5da04a090a39f9eb4012086ff5aa24abfb10cd1584642581f' 
  AND token = 'hc4/MleRciHb55P2Hi/fnQtB6i+oTA4Fj4kXt1xe4so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}