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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c4187bdd6e8e931e9e011f37971381c1c7617d10f9d739f1c017baabbfab2ca' 
  AND token = 'p+b1bMs/ki0Pa9fwMTS+8FTAvpmGmZ2WyforIu21PcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}