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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc887f51ffa247dee6e61e425d89a316e52857d379271a828e4da42d4805aee' 
  AND token = 'u/spHD6hY9eG5dPFRvFg4Plo2E5ygDrwxmmqdZtDBRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}