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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cf5c156673c17b2f3fce5fa2b0cb0746743cc992e04649704101c3ddd0f6315' 
  AND token = '4WiWCjsDJWswOuzGEwW8zHtkvXJakhnL7WwdMffFYT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}