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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b59ac0c13b499303b0ac1d298b3ba2a37887bf06beba900b4e91067683bc61' 
  AND token = 'VaQg4N/N/JjCDTQyu9wxKUpWjAhfUpF2pXq6qeHOeUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}