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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a0dd8edb45b0c5c62b59dbbd6d85efe0a41631e9bdaacd691546e446673af9' 
  AND token = 'ozIDavGdvuGPpsHKQChnGMJhOYhc0/F4NGOYQBi3sg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}