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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781cfa514f9b3e6f0ae8ecdc7779aa6f59817a298bdb35c97bf8a800e9430afe' 
  AND token = 'r08+DX0BSi1cP2idoMkXhGhqO4nCAjegvKLipHRC9y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}