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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c5397623d26b1a30a3803480eb57cd9c5f3546c107cc39675ceee20a7cf276' 
  AND token = 'dvrVFoUpLaO/b7x0+8RcpAcWWaDXxlj1KDzSswDM4m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}