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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9844f3712a1aa01688501a30a91ea39b0ebdddc91fb4e9bbb1dc7be566d485' 
  AND token = 'cabyYKiQnsLgfA+cidBSq6wmUqCq4rPwjc4ExEMFh/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}