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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f001e81206be66015166a1fbd54b535b9cbf25af9b0628ce21770652532c1b2c' 
  AND token = 'wP1IG9RImy7gnfhXU1ZLnkQVfdIOzf8LRat6eDqqGXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}