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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd02b83a5ca02961cedb5fa22fe2408ff3bef2041fba764c97495393a9534fc' 
  AND token = 'jQlbcK1vUYNnAVo8No843BSdwXEykq2oR2TRcNa2Wig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}