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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d0509142e01eeb3f212709337aa424f480d988873d5754394d0df83869d39d' 
  AND token = '83+2lGyVvF/B40nF4UR9ibBSCXFu2BVwxxu+GzQsLj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}