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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba5161f8efc1f8e3eaa107c37b8debf3b8defe0d333121cc6ef1d81a2e965cc' 
  AND token = 'k6m1LvZSFb3PtM80dAWUDjWrw8q/AdashR8PCETTOeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}