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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1043ea759a24757f6c5a372cfcb865844beaaacb8c3b7776db0448b7510a9c' 
  AND token = '9r/JIx0Gue6r+PceRaaEO/DVJdDdmhlOYs9pCHfZlM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}