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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1d7cdf4120bd6daba83b4794226d33d76278caa6b6c3ae7b6800ac701f4f074' 
  AND token = 'UAzuFYQLFI7d4l/YWIyxp3fFiX3bMOF7kR3cLHwdARM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}