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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b793abd9a4e22be369ed7d348320c9d1446115fc124f846fe03e6df0777d583' 
  AND token = 'Csb0eleWmFSl1d+uxdP8jgdOzf4O1vEoyuYDkRZoS9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}