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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6686d8da9989e9d50debf5b5d84f00fdfcd6de4c1565a90f71a7d15de26cd558' 
  AND token = 'HOUImZcaHFd4BIOFuMiTNAhdbQpnCODW4u0rC5u8ZFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}