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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6947cd89008dd33607956005fb71c3466c2a44dc27e92a748d90d1e545f05c63' 
  AND token = 'V+71owIcccrwHLFLRG5akIQWReaILieAQhyAyrxV4wE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}