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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37a4fcfea0f05af5c6cad18f8f315a15f87cde2ebc59384e9a8df81e60bd486' 
  AND token = 'MyB2drFIUQ0C3isXd7f5b8ejzzrYaWaGDwe01G8mHxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}