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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e3733fc13f32405803ec2e8f7c47372d38ea9576616153770bf51d5d4094a1' 
  AND token = 'WWSNoL38LGoofLA0a81vTGpnXT8xM8lmRukx38SDKhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}