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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7ce32278c1bf122d2c0ee08fec1d1bd452e0a8c625c66db3a80ed936683337' 
  AND token = 'jD9seF91+JHa4e8NMC5PA1SCZ/PDJwk6BCL4YS+7DOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}