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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec3cdc97a6c9a13b39b05da8de406749f6c4ce215503b178a8a96ee7e6d5995' 
  AND token = 'OT5+M61BVl/NmmMGRqi3qsQPwZ6vEKRRPpcKQN1rxO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}