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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a46c8b6eda9d68c281798f3a3d28764d867a5f8f32ce4b068a1f81df3077b42' 
  AND token = 'fb+E87pWWrUzCAjxJGHD08rFueeHNaKgBdp/Cf/hCAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}