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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22da149a179b58bb74ad73aa1929724a8200024426bce3dcf095835f2f46b6a' 
  AND token = 'OkHYZpaHeLISphnXxB6o6NUO7xRGDnZV1LZI8SntIC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}