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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac4ef85946eaec9f0b2bcba8523f8c5ecfb56f741a9611d26c6a318cda04646' 
  AND token = 'WfPco1SC4rsxq/mtLU2PHnAsLU9DBd9dqpoaBm6FWG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}