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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef07e252072e3b1d95a09d15faec435b6d5fc1db7062b2cfab141508e9bd501' 
  AND token = 'gP46AAYGz7IJ+vBrkVkgLIQztG4Sc3bMxODcGF4BE3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}