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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5249ea5564ce9b0c163e5108c6f7e2c4f752515a1c1f950987239886ffc4a785' 
  AND token = 'mjyQ/mME7V+E/PQ3oggctxXgGB/2D6T7c1E4CV4iV70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}