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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224b7cfcd0a98bfd0a554c8888e8ae3c0818581849eb0733e46a9556263b507f' 
  AND token = 'qAvrD8XnQdeaE14jVS9Af+MVVPDWu+k2ar8cwFl5bBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}