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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38eb7678a6a4bfec1e092dd4d2cf906d8a799eaa536cb910d025b57916a3bb3a' 
  AND token = 'QCe5IuFhE6xS6Y0+PqL217dA1dkOpdL5rgHkujj2OIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}