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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a770260d913a1af9168915e3fcef28426b3b75aa37c2d1d74b5f562021ade702' 
  AND token = 'k8242+w8Ze1dFVBj0oF+RU0V0gnmtkRRma6/L4q4XBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}