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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb5783c3fdb54eb824df1e26c0dc6c3e4ef0a9219e13a019c674cbf27d8e12c' 
  AND token = 'w+DCO08Via1xHIBEhYllAuy7uO7tSy6jC2Ta+ixCDs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}