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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8e45a8f137defaf67b3ff2682eab860e01a7bb0d3c414a2603619df86a648c' 
  AND token = 'f3GqHxMfvlRBjSgpZrt84+OhahRUiPxQ9n7ns2SdB7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}