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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5146bd28e9ff1ef3ef36ce55fbb5de760b576f6ca500d2e9c6ebd2c6af49da60' 
  AND token = 'ZSE8sDAOX9qpqYcXPWS+jANnodJv49zGocZueK58f+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}