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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea88937a8ffe22923874e756f9658bcf4c4e356c1397f2d0df6e628eecaee636' 
  AND token = '/3qoNdcrP2zwfv/UsOIA7i00UehRGD+eQt31e/JZLAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}