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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8f8644474e553d208ec9f5d37c1fcd422463e1e86379f5d2f79dc4dc6fcb4b' 
  AND token = 'jpDS5gT6DXzlMIFIM4qUywUx+abkXp4H+YqUGheAmss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}