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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666b6218e88eaf7ea992fd54db259f785ff4a829124b807cbf2da63daea97c0e' 
  AND token = '+ABCUD1MtBC6byI12SC0G0ArJZ7u2+ME2ehb7LWBcys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}