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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea3b48c296861c5002cedfb411edc9331b77a433923ed04baf3165bfaa430af' 
  AND token = 'yNx13L32h9At9kCvM2LN1AS/663+V4wzaSZmR0Rj+jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}