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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499e6da0e88a2b3ffae412ed69dbf9c7e65b5ff03e534eb85a5cb492d52d236c' 
  AND token = 'XEx0nHRCerLoQMo/K2QF3khQcjyXxtgtIfuWrq800ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}