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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf5948cf3995a2a8b58b55e2c85b3f6718b616505848c6a151e14ada801c22a' 
  AND token = '+1/OD0+xUJ9qNkAxKn3Tm0b842Qt375VixYhmmgmmpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}