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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8eed9501e62ee189464f1cfd3d6f8699b2e8d5b39112bbb0fd07c68869e018' 
  AND token = 'HW2Ph0CJk12IwkFcdXLooLe532KuimTLAkvv+ChIh6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}