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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff0505aaa3360d7256345e994b62cfffe27d808160681c31d140783df582f35' 
  AND token = 'P91Lgy6BLML5S990Lg5gNkoatmE7ySoMCkkrphsh2hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}