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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0345c9b7ff627235f1dcca6bc081cde9614cb02f988a1b2bee96d1bf248d58' 
  AND token = 'xaTL+kAUTJ10uXod612AD7IQApyYZQ6HLTyImeci248=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}