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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa7ef9c502f88f84d82e35a3a1ba8beb019bde667e3352cc3f5957146c41ef2' 
  AND token = '/1d3oPW/Vn7GGIk7+6FLTL1Jiy6dCsjFlVVrUwPf69k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}