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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd000734ca729cd033ca7436355fd9eac01cdfde19d08acf87ac281095937cc1b' 
  AND token = 'HfEpOnH40cSct++9I4vNUouQwRJL0sXTci++/xfDh4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}