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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e8bf9c760654c7db041aa30df0d4599d9e5ef042ffeeb76e2a81de5825cd8a' 
  AND token = 'OoI9y/voL7a3o0eXiGzsql+tyAbAU5o/FAH0D3KVRV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}