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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e6f38e92b6ff2b1e30d9550736fc24e52b363030586edbb4f4e39546de2ee6' 
  AND token = 'iy091klB3YxeCT2fQ1bTagV9AnpwEqNVgZTRmeItvOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}