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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b06c15bc9facb9c61efc00120fad2a8b83ce4c464be0980405ac0d174000ab8' 
  AND token = 'XkFLpL+eCCdC4CRXgzfgQn85Nb9knYOLgYLwc6Gp0tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}